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Prévalence du Cytomégalovirus chez les Donneurs de Sang d’un Hôpital de District Urbain à Douala-Cameroun
| Content Provider | Semantic Scholar |
|---|---|
| Author | Essomba, Noel Emmanuel Ngaba, Gp Koum, Danielle Christiane Kedy Momo, Linda Coppieters, Yves |
| Copyright Year | 2015 |
| Abstract | RESUME INTRODUCTION. Le cytomegalovirus humain peut etre cause de mortalite et de morbidite chez les sujets immunodeprimes et chez les nouveau-nes. Le but de cette etude etait de determiner sa prevalence chez les donneurs de sang recus a l’hopital de district de Bonassama a Douala. PATIENTS ET METHODES. Il s’agit d’une etude transversale menee de fevrier a avril 2014. Tous les sujets ont ete depistes au cytomegalovirus et ont egalement beneficie des tests de VIH, hepatite B, hepatite C et Syphilis. Les anticorps anti-cytomegalovirus ont ete recherches par la methode ELISA. RESULTATS. Au total, 167 donneurs ont ete inclus dans ce travail. L’âge moyen etait de 31,5 ± 8,5 ans, avec un sexe ratio H/F de 5,18. On rencontrait deux types de donneurs ; les benevoles (4,1%), et familiaux (95,8%). La prevalence du CMV enregistree a ete de 98,8%. Les donneurs du groupe O ont ete les plus representatifs avec 53,8%. Les autres prevalences ont ete les suivantes : VIH 19 (11,3%) ; VHB 20 (11,9%) ; VHC 5 (2,9%) ; Syphilis 7 (4,1%). Tous les patients VIH positifs ont presente une infection a cytomegalovirus. CONCLUSION. La prevalence du cytomegalovirus est tres elevee au sein de la population des donneurs. Ce virus ne faisant pas l’objet d’un depistage systematique en banque de sang, des etudes prospectives pourront evaluer le risque lie au CMV apres une transfusion sanguine surtout chez les patients immunodeprimes. SUMMARY INTRODUCTION. Human cytomegalovirus may be cause of mortality and morbidity in immunocompromised subjects and in newborns. The aim of this study was to determine the prevalence among blood donors received in Bonassama district hospital in Douala. PATIENTS AND METHODS. This was a cross-sectional study conducted from February to April 2014. All subjects were screened for CMV and also received HIV testing, HBV, HCV and syphilis. Anti CMV antibodies were detected by ELISA method. RESULTS. A total of 167 donors were included. The mean age was 31.5 ± 8.5 years, with a sex ratio M / F of 5.18. There were two types of donors: volunteers (4.1%), and family (95.8%). The overall prevalence of CMV was 98.8%. The group O donors were the most representative with 53.8%. Other prevalence’s were as follows: HIV 19 (11.3%); HBV 20 (11.9%); HCV 5 (2.9%); Syphilis 7 (4.1%). All HIV-positive patients had cytomegalovirus infection. CONCLUSION. The prevalence of cytomegalovirus is very high in the donor population. This virus is not subject to systematic screening in blood banks, so prospective studies are needed to assess the risk associated with CMV after a blood transfusion especially in immunocompromised patients. |
| File Format | PDF HTM / HTML |
| Volume Number | 16 |
| Alternate Webpage(s) | http://www.hsd-fmsb.org/index.php/hsd/article/download/488/pdf_248 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
