Loading...
Please wait, while we are loading the content...
Similar Documents
Developmental and application of insulin infusion profiles for therapy of type-I diabetics with portable insulin infusion systems.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Schulz, Gunnar Strack, Thomas Beyer, J. Krause, Ulrich Cordes, U. Weber, Thomas Nagel, J. Beutelspacher, F. |
| Copyright Year | 1984 |
| Abstract | We studied the insulin requirements of seven insulin-dependent diabetics applying a glucose controlled insulin infusion system. The data were transformed into individually programmed and rectangular profiles. The MAGE, a measure of blood sugar fluctuations, was significantly lower when individually programmed step profiles were used (P less than 0.005) than it was when rectangular profiles were applied: 57.7 +/- 24.8 mg/dl vs 89.0 +/- 42.9 mg/dl. The average of measured blood glucose levels was significantly lower in individually programmed infusion profiles (P less than 0.025). The combination of individually programmed profiles and preprandial insulin bolus significantly reduced the postprandial blood glucose level and increase (P less than 0.001). Our investigations suggest that individually programmed insulin infusion profiles are able to smooth blood glucose fluctuations. When combined with an initial insulin bolus they may lead to a reduced insulin consumption after meals. |
| Starting Page | 189 |
| Ending Page | 200 |
| Page Count | 12 |
| File Format | PDF HTM / HTML |
| DOI | 10.18419/opus-7186 |
| PubMed reference number | 6503348 |
| Journal | Medline |
| Volume Number | 2 |
| Issue Number | 3 |
| Alternate Webpage(s) | http://elib.uni-stuttgart.de/bitstream/11682/7203/1/nag6.pdf |
| Alternate Webpage(s) | https://doi.org/10.18419/opus-7186 |
| Journal | Life support systems : the journal of the European Society for Artificial Organs |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
