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Hemodynamic profile after the Norwood procedure with right ventricle to pulmonary artery conduit.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Pizarro, Christian Januszewska, Katarzyna Malec, Edward |
| Copyright Year | 2003 |
| Abstract | BACKGROUND The balance of systemic, pulmonary, and coronary blood flow after the Norwood operation for hypoplastic left heart syndrome (HLHS) is critical to early survival. We hypothesized that a right ventricle to pulmonary artery conduit (instead of a systemic to pulmonary artery shunt) would result in hemodynamic changes consistent with a more stable balance of systemic, pulmonary, and coronary perfusion. METHODS AND RESULTS Hemodynamic data were obtained during cardiac catheterization before the hemi-Fontan procedure from 24 patients with HLHS; the first 10 had a Norwood operation with a systemic to pulmonary artery shunt, and the latter 14 had the Norwood operation with a right ventricle to pulmonary artery conduit. Significant differences were present, with the right ventricle to pulmonary artery conduit group having a higher aortic diastolic pressure (55 versus 42 mm Hg), a narrowed systemic pulse pressure (43 versus 64 mm Hg), a lower Qp:Qs (0.92 versus 1.42), a higher coronary perfusion pressure (46 versus 32 mm Hg), and a higher ratio of pulmonary artery diameter to descending aorta diameter (1.51 versus 1.37). CONCLUSIONS We conclude that, in HLHS after the Norwood operation, the right ventricle to pulmonary artery conduit modification produces hemodynamic changes consistent with improved coronary perfusion and a more favorable distribution of systemic, pulmonary, and coronary blood flow. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://circ.ahajournals.org/content/circulationaha/108/7/782.full.pdf?download=true |
| PubMed reference number | 12912806v1 |
| Volume Number | 108 |
| Issue Number | 7 |
| Journal | Circulation |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anastomosis of pulmonary-subclavian artery by Blalock-Taussig operation Descending aorta Diameter (qualifier value) Diastole Diastolic blood pressure Heart Ventricle Hemi Hemodynamics Hypoplastic Left Heart Syndrome Idiopathic Pulmonary Fibrosis Intracranial Hypertension Left side of heart Norwood Operation Patients Pulmonary artery structure Right ventricular structure |
| Content Type | Text |
| Resource Type | Article |
