NDLI: The Effect of Silk Membrane Plus 3% 4-hexylresorcinol on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

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The Effect of Silk Membrane Plus 3% 4-hexylresorcinol on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

Content Provider	Semantic Scholar
Author	Seok, Hyun Lee, Sang Woon Kim, Sophie Seo, Dong Hyun Kim, Han Sung Kweon, Hae Yong Jo, You Young Kang, Tae Yeon Lee, Myungjin Chae, Weon Sik
Copyright Year	2013
Abstract	The objective of this study was to evaluate the bone regeneration capability of silk membrane plus 3% 4-hexylresorcinol (3% 4-HR plus SM) in a rabbit calvarial defect model. Twenty New Zealand white rabbits were used in this study. Bilateral round shaped defects were created in the parietal bone (diameter: 8.0 mm). And the defects were covered with (1) 3% 4-HR plus SM, (2) collagen membrane (CM), (3) no graft material. After surgery, the animals were sacrificed at 4 weeks and 8 weeks. Bone regeneration was analyzed in each section by micro-computerized tomography (μ-CT). And Hematoxylin and eosin stains were used for histological analysis. As measured by μ-CT analysis 4 weeks after surgery, the average of new bone formation in animals treated with 3% 4-HR plus SM was greater than that of animals treated with CM. and the difference was statistically significant. And well organized lamella bones were observed in the histological view of the 3% 4-HR plus SM group. Therefore, more bone regeneration was seen in animals treated with 3% 4-HR plus SM than in those treated with CM or uncovered control.
Starting Page	209
Ending Page	217
Page Count	9
File Format	PDF HTM / HTML
DOI	10.7852/ijie.2013.27.1.209
Volume Number	27
Alternate Webpage(s)	http://ocean.kisti.re.kr/downfile/volume/ksss/E1IEAM/2013/v27n1/E1IEAM_2013_v27n1_209.pdf
Alternate Webpage(s)	http://210.101.116.28/W_files/ftp42/0n601822_pv.pdf
Alternate Webpage(s)	https://doi.org/10.7852/ijie.2013.27.1.209
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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