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Prevalence of melanocortin receptor 4 (MC4R) V103I gene variant and its association with obesity among the Kampar Health Clinic cohort, Perak, Malaysia.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chua, Hui Na |
| Copyright Year | 2012 |
| Abstract | This study investigated the prevalence of the Melanocortin receptor 4 (MC4R) V1031 gene variant and its association with obesity among a cohort of 254 patients (101 males; 118 obese) attending the Kampar Health Clinic. Genotyping revealed the mutated I allele frequency of 0.02, no homozygous mutated (II), and similar distribution of V and I alleles across BMI groups, genders and ethnic groups. No significant difference was found for the means of anthropometric measurements between alleles. Prevalence of this gene variant among the Malaysian cohort was similar with previous populations (2-4% of mutated allele carrier), but was not associated with obesity. |
| File Format | PDF HTM / HTML |
| PubMed reference number | 22822657 |
| Journal | Medline |
| Volume Number | 67 |
| Issue Number | 2 |
| Alternate Webpage(s) | http://www.e-mjm.org/2012/v67n2/melanocortin-receptor-4.pdf |
| Journal | The Medical journal of Malaysia |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
