NDLI: Tandem [5+1] annulation-isocyanide cyclization: efficient synthesis of hydroindolones.

Content Provider	Semantic Scholar
Author	Wang, Hwai-Chiuan Zhao, Yu-Long Ren, Chuan‐ Qing Diallo, Aboubacar
Copyright Year	2011
Abstract	A new strategy for the rapid construction of functionalized reduced indoles starting from activated methylene isocyanides and 1,5-dielectrophilic 5-oxohepta-2,6-dienoates (and their equivalents) through a [5+1] annulation-isocyanide cyclization cascade under basic conditions has been developed. This strategy allows the synthesis of polysubstituted dihydroindolones and tetrahydroindolones in high to excellent yields under extremely mild conditions in a single step.
File Format	PDF HTM / HTML
DOI	10.1039/c1cc14916d
PubMed reference number	22011962
Journal	Medline
Volume Number	47
Issue Number	45
Alternate Webpage(s)	http://www.rsc.org/suppdata/cc/c1/c1cc14916d/c1cc14916d.pdf
Alternate Webpage(s)	https://doi.org/10.1039/c1cc14916d
Journal	Chemical communications
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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