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Síndrome de hiperinfección por Strongyloides stercoralis: diagnóstico por medio de citología de lavado broncoalveolar
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fernández, Liliana González, Alejandro Sua, PhDc. Luz Fernanda Vargas, Diego Alejandro Barragán Muñoz, Carlos Andrés Unigarro |
| Copyright Year | 2015 |
| Abstract | Introduction: Strongyloides stercoralis (Ss) is a parasite that causes severe infections, especially in immunocompromised patients; hyperinfection syndrome is one of its most serious manifestations. Early detection is vital for initiating adequate therapy. In this sense, bronchoscopy and bronchoalveolar lavage cytology are useful tools for early diagnosis. Patients and methods: retrospective review of cases of Ss hyperinfection syndrome diagnosed by bronchoalveolar lavage cytology at the Fundacion Valle del Lili, Cali over the period from 2004 to 2012; 8 cases were found; we describe the demographic and clinical characteristics, risk factors, findings, and outcomes, and carry out a review of the literature. Results: 7 male (88%) and 1 female (12%) cases were found, the mean age was 48 years, 2 patients (22%) had HIV infection, 3 patients had chronically taken steroids (heart transplant, SLE nephritis, and chemotherapy) (33%), 2 patients were severely malnourished, 2 patients had positive human T-cell lymphotropic virus (HTLV-1). None of the patients had eosinophilia. All were treated with ivermectin and broad spectrum antibiotics in order to cover Gram-negative bacteremia (33% had positive cultures). In-hospital mortality was 62,5%. Conclusion: hyperinfection syndrome is a severe complication of Ss infection in immunocompromised patients. Despite great deterioration of the patient's general condition, its clinical presentation is not specific. A high index of clinical suspicion is necessary for diagnosis and timely therapy. In these cases, bronchoalveolar lavage cytology is a useful tool form identifying the organism. |
| File Format | PDF HTM / HTML |
| DOI | 10.30789/rcneumologia.v27.n4.2015.69 |
| Volume Number | 27 |
| Alternate Webpage(s) | https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/69/66 |
| Alternate Webpage(s) | https://doi.org/10.30789/rcneumologia.v27.n4.2015.69 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
