Dialectical behaviour therapy for post-traumatic stress disorder after childhood sexual abuse in patients with and without borderline personality disorder: a randomised controlled trial.

Content Provider	Semantic Scholar
Author	Bohus, Martin Dyer, Anne Sibilla Priebe, Kathlen Krüger, Antje Kleindienst, Nikolaus Schmahl, Christian Niedtfeld, Inga Steil, Regina
Copyright Year	2013
Abstract	BACKGROUND Post-traumatic stress disorder (PTSD) with co-occurring severe psychopathology such as borderline personality disorder (BPD) is a frequent sequel of childhood sexual abuse (CSA). CSA-related PTSD has been effectively treated through cognitive-behavioural treatments, but it remains unclear whether success can be achieved in patients with co-occurring BPD. The aim of the present study was to determine the efficacy of a newly developed modular treatment programme (DBT-PTSD) that combines principles of dialectical behaviour therapy (DBT) and trauma-focused interventions. METHODS Female patients (n = 74) with CSA-related PTSD were randomised to either a 12-week residential DBT-PTSD programme or a treatment-as-usual wait list. About half of the participants met the criteria for co-occurring BPD. Individuals with ongoing self-harm were not excluded. The primary outcomes were reduction of PTSD symptoms as assessed by the Clinician-Administered PTSD Scale (CAPS) and by the Posttraumatic Stress Diagnostic Scale (PDS). Hierarchical linear models were used to compare improvements across treatment groups. Assessments were carried out by blinded raters at admission, at end of treatment, and at 6 and 12 weeks post-treatment. RESULTS Under DBT-PTSD the mean change was significantly greater than in the control group on both the CAPS (33.16 vs. 2.08) and the PDS (0.70 vs. 0.14). Between-group effect sizes were large and highly significant. Neither a diagnosis of BPD nor the severity or the number of BPD symptoms was significantly related to treatment outcome. Safety analyses indicated no increase in dysfunctional behaviours during the trial. CONCLUSION DBT-PTSD is an efficacious treatment of CSA-related PTSD, even in the presence of severe co-occurring psychopathology such as BPD.
Starting Page	1139
Ending Page	1140
Page Count	2
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.safetylit.org/citations/ild_request_form.php?article_id=citjournalarticle_401635_20
Alternate Webpage(s)	https://www.safetylit.org/citations/ild_request_form.php?article_id=citjournalarticle_401635_28
PubMed reference number	23712109v1
Alternate Webpage(s)	https://doi.org/10.1159/000348451
DOI	10.1159/000348451
Journal	Psychotherapy and psychosomatics
Volume Number	82
Issue Number	4
Language	English
Access Restriction	Open
Subject Keyword	Blinded Borderline Personality Disorder Exclusion Nevus sebaceous Patients Personality Disorders Physiological Sexual Disorders Post-Traumatic Stress Disorder Psychopathology Self injury Stress Disorders, Traumatic Wounds and Injuries dialectical behavior therapy high-grade childhood cerebral astrocytoma
Content Type	Text
Resource Type	Article