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Off-pump versus on-pump coronary artery bypass surgery in patients with triple-vessel disease and enlarged ventricles
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yu, Lei Gu, Tianxiang Shi, Enyi Wang, Chun-lei Fang, Qin Yu, Yang Zhao, Xiaoqi Qian, Cheng |
| Copyright Year | 2014 |
| Abstract | BACKGROUND AND OBJECTIVES Off-pump coronary artery bypass grafting (OPCAB) is a popular treatment for patients with ischemic heart disease, especially for high-risk patients. However, whether OPCAB can lead to better clinical outcomes than on-pump coronary artery bypass grafting (ONCAB) in patients with enlarged ventricles remains controversial. This prospective randomized study was designed to characterize comparison of early clinical outcome and mid-term follow-up following ONCAB versus OPCAB in patients with triple-vessel disease and enlarged ventricles. DESIGN AND SETTINGS Prospective randomized trial of patients treated at The First Affiliated Hospital, China Medical University, over a 3-year period (2007-2010). METHODS A total of 102 patients with triple-vessel disease and enlarged ventricles (end-diastolic dimension >=6.0 cm) were randomized to OPCAB or ONCAB between July 2007 and December 2010. The in-hospital out.comes were analyzed. The study included a mid-term follow-up, with a mean follow-up time of 49.40 (12.88 months). RESULTS No significant differences were recorded in the baseline clinical characteristics of ONCAB and OPCAB groups. A statistical difference was found between the two groups at the time of extubation, intensive care unit stay, hospital stay, blood requirements, incidence of intra-aortic balloon pump support, pulmonary complications, stroke, reoperation for bleeding, and inotropic requirements > 24 hours (P < .05). The number of anastomoses performed per patient, the incidence of postoperative ventricular arrhythmia, myocardial infarction, new-onset atrial fibrillation, hemodialysis, infective complications, recurrent angina, and percutaneous reintervention were similar between the 2 groups (P > .05). The left ventricular end-diastolic dimension was significantly smaller at 6 months' follow-up in the 2 groups than it was before operation ( < .05). No differences in hospital mortality and mid-term mortality between OPCAB and ONCAB groups were found. During the follow-up, no patient in either group had undergone repeat coronary artery bypass grafting. CONCLUSION No differences in early and mid-term mortality were found between OPCAB and ONCAB in patients with triple-vessel disease and enlarged ventricles. However, OPCAB seems to have a beneficial effect on postoperative complications. |
| Starting Page | 222 |
| Ending Page | 228 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| PubMed reference number | 25266182v1 |
| Alternate Webpage(s) | https://doi.org/10.5144/0256-4947.2014.222 |
| DOI | 10.5144/0256-4947.2014.222 |
| Journal | Annals of Saudi medicine |
| Volume Number | 34 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Angina Pectoris Aortic Valve Insufficiency Atrial Fibrillation Cerebral Ventricles Cerebrovascular accident Coronary Artery Bypass Surgery Diastole Enlargement procedure Follow-Up Report Heart Atrium Heart Diseases Heart Ventricle Hemodialysis Hemorrhage Myocardial Infarction Myocardial Ischemia Paget's Disease, Mammary Patients Postoperative Complications Repeat Surgery Small Tracheal Extubation Transplanted tissue Ventricular Fibrillation intensive care unit pulmonary complications |
| Content Type | Text |
| Resource Type | Article |
