NDLI: Facile one-pot synthesis of unsymmetrical ureas, carbamates, and thiocarbamates from Cbz-protected amines.

Content Provider	Semantic Scholar
Author	Kim, Hee-Kwon Lee, Anna Suk Yee
Copyright Year	2016
Abstract	A novel one-pot synthesis of unsymmetrical ureas, carbamates and thiocarbamates from Cbz-protected amines has been developed. In the presence of 2-chloropyridine and trifluoromethanesulfonyl anhydride, isocyanates are generated in situ, which facilitate rapid reaction with amines, alcohols, and thiols to afford the corresponding ureas, carbamates and thiocarbamates in high yields.
File Format	PDF HTM / HTML
DOI	10.1039/c6ob01290f
Alternate Webpage(s)	http://www.rsc.org/suppdata/c6/ob/c6ob01290f/c6ob01290f1.pdf
PubMed reference number	27406041
Alternate Webpage(s)	https://doi.org/10.1039/c6ob01290f
Journal	Medline
Volume Number	14
Issue Number	30
Journal	Organic & biomolecular chemistry
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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