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A Facile Method of Preparing l-α-Methyl DOPA (l-3-(3,4-Dihydroxyphenyl)-2-methylalanine)
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yamada, Shigeki Hongo, Chikara Yamamoto, Masao Chibata, Ichiro |
| Copyright Year | 1976 |
| Abstract | To develop a practical method for production of l-α-methyl DOPA, the optical resolution of its precursor, dl-3-(3,4-methylenedioxyphenyl)-2-methylalanine, was studied. The monohydrochloride of dl-3-(3,4-methylenedioxyphenyl)-2-methylalanine was resolved by a preferential crystallization procedure. Optically pure l-α-methyl DOPA was obtained in good yield. Industrial production of l-α-methyl DOPA by the present simple method is considered to be very promising. |
| Starting Page | 1425 |
| Ending Page | 1427 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1080/00021369.1976.10862214 |
| Volume Number | 40 |
| Alternate Webpage(s) | https://www.jstage.jst.go.jp/article/bbb1961/40/7/40_7_1425/_pdf |
| Alternate Webpage(s) | https://doi.org/10.1080/00021369.1976.10862214 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |