NDLI: Influences of nano-TiO2 on the neurotoxicity induced by galaxolide in the polychaeta Perinereis aibuhitensis

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Influences of nano-TiO2 on the neurotoxicity induced by galaxolide in the polychaeta Perinereis aibuhitensis

Content Provider	Semantic Scholar
Author	Qian-Ru, Zhang Wen-Yan, Mu Jian-Mei, Wang Si-Wen, Li
Copyright Year	2018
Abstract	Influences of nano-TiO2 on the neurotoxicity induced by galaxolide in the polychaeta Perinereis aibuhitensis ZHANG Qian-ru1, 2, JIANG Li-si1, 3, MU Wen-yan1, 3, WANG Jian-mei1, 3, LI Si-wen1 (1.Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China; 2.Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Guangzhou 510275, China; 3.University of Chinese Academy of Sciences, Beijing 100049, China) Abstract:The number of reports on the ecotoxicological effects of emerging contaminants, especially emerging organic and inorganic com原 bined contaminants, on estuary keystone species(polychaeta)is low. To understand the influence of these contaminants better, the relation原 ships between toxicological indices(mortality and acetylcholinesterase(AChE)activity)and concentrations of contaminants(galaxolide (HHCB)and nano-TiO2)were examined in Perinereis aibuhitensis under laboratory conditions. The results of single contaminant stress in原 dicated that the contaminants potentially were physiologically toxic to P. aibuhitensis . The estimated LC50 (8 d)for HHCB and nano-TiO2 derived from the relationships between mortality and single contaminant concentrations were 313.21 mg·L-1 and 27.09 mg·L-1, respectively. The AChE activity of P. aibuhitensis was decreased, namely, the inhibition rate of AChE increased with an increase of the single HHCB ex原 posure concentrations. However, the AChE activity of combined contaminants was significantly lower than that of single HHCB stress owing to the addition of nano-TiO2. The results implied that nano-TiO2 enhanced the sensitivity of AChE to HHCB, which exacerbated the neuro原
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.aes.org.cn/nyhjkxxb/ch/reader/create_pdf.aspx?file_no=20180407&flag=1&journal_id=nyhjkxxb&year_id=2018
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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