NDLI: Two new megastigmane glycosides, physanosides A and B, from Physalis alkekengi L. var. franchetii, and their effect on NO release in macrophages.

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Two new megastigmane glycosides, physanosides A and B, from Physalis alkekengi L. var. franchetii, and their effect on NO release in macrophages.

Content Provider	Semantic Scholar
Author	Zhao, Feng Liu, Hongwei Chen, Lixia Jiang, Zhihu Liu, Hongxia Wang, Naili Yao, Xinsheng Qiu, Feng
Copyright Year	2008
Abstract	Two new megastigmane glycosides, physanosides A and B (1 and 2, resp.), were isolated from Physalis alkekengi L. var. franchetii, together with four known compounds (6S,9R)-roseoside (3), (6S,9S)-roseoside (4), (6R,9S)-3-oxo-alpha-ionol beta-D-glucopyranoside (5), and citroside A (6). Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, high-resolution mass spectrometry, and CD spectroscopy, and their inhibitory effect on NO production was also examined. Compounds 2 and 3 exhibited strong inhibition on lipopolysaccharide-induced NO release by macrophages with IC(50) values of 9.93 and 7.31 microM, respectively.
File Format	PDF HTM / HTML
DOI	10.1002/cbdv.200890072
PubMed reference number	18493962
Journal	Medline
Volume Number	5
Issue Number	5
Alternate Webpage(s)	http://www.doc-developpement-durable.org/file/Culture-plantes-a-petits-fuits-sucres/physalis-alk%C3%A9kenge/Two%20New%20Megastigmane%20Glycosides,%20Physanosides%20A%20and%20B,%20from%20Physalis%20alkekengi.pdf
Alternate Webpage(s)	https://doi.org/10.1002/cbdv.200890072
Journal	Chemistry & biodiversity
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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