NDLI: Urinary Metabolites of Chloroprocaine Studied by Combined Gas Chromatography

Content Provider	Scilit
Author	Krohg, Knut Jellum, Egil
Copyright Year	1981
Description	Journal: Anesthesiology The purpose of this study was to identify the metabolic pathway of 2-chloro-4-aminobenzoic acid (CABA), a primary metabolite of chloroprocaine. Urine was collected from 4 healthy, pregnant women following the epidural administration of 600 mg chloroprocaine. The urinary metabolites were extracted with ether and identified and quantitatively estimated with a gas chromatography--mass spectrometry instrument. The analysis showed that CABA is converted to N-acetyl-CABA and subsequently excreted in the urine.
Related Links	https://pubs.asahq.org/anesthesiology/article-pdf/54/4/329/302790/0000542-198104000-00014.pdf
Ending Page	332
Page Count	4
Starting Page	329
ISSN	00033022
e-ISSN	15281175
DOI	10.1097/00000542-198104000-00014
Journal	Anesthesiology
Issue Number	4
Volume Number	54
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	1981-04-01
Access Restriction	Open
Subject Keyword	Journal: Anesthesiology Biochemical Research Mass Spectrometry Gas Chromatography
Content Type	Text
Resource Type	Article
Subject	Anesthesiology and Pain Medicine

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Urinary Metabolites of Chloroprocaine Studied by Combined Gas Chromatography—Mass Spectrometry