Fitness, Fatness, Physical Activity, and Autonomic Function in Midlife

Content Provider	Scilit
Author	Kiviniemi, Antti M. Perkiömäki, Nelli Auvinen, Juha Niemelä, Maisa Tammelin, Tuija Puukka, Katri Ruokonen, Aimo Keinänen-Kiukaanniemi, Sirkka Tulppo, Mikko P. Järvelin, Marjo-Riitta Jämsä, Timo Huikuri, Heikki V. Korpelainen, Raija
Copyright Year	2017
Description	Journal: Medicine & Science In Sports & Exercise
Abstract	Purpose Although low cardiorespiratory fitness (CRF), physical inactivity, and obesity are associated with impaired autonomic function, they are also extensively interrelated. The present study aimed to assess the extent to which they contribute to autonomic function independently of each other. Methods At the age of 46 yr, 1383 men and 1761 women without cardiorespiratory diseases and diabetes underwent assessments of vagally mediated heart rate (HR) variability (root mean square of successive differences in R-R interval (rMMSD)), peak HR during a submaximal step test (CRF), and 60-s HR recovery (HRR). Moderate-to-vigorous physical activity (MVPA; ≥3.5 METs, 2 wk) was measured by wrist-worn accelerometer and body fat percentage (Fat%) by bioimpedance. Results In men, CRF and Fat% were significantly associated with higher rMSSD (standardized β = 0.31 and −0.16) and HRR (β = 0.19 and −0.18), whereas higher MVPA was linked with higher HRR (β = 0.13) when including CRF, MVPA, and Fat% in the initial regression. After adjustments for other lifestyle and cardiometabolic factors, CRF remained significantly associated with rMMSD (β = 0.24) and HRR (β = 0.14), as did MVPA with HRR (β = 0.11). In women, CRF was associated with rMSSD (β = 0.23) and HRR (β = 0.15), and MVPA (β = 0.17) and Fat% (β = −0.07) with HRR, when CRF, MVPA, and Fat% were adjusted for each other. After further adjustments, CRF remained a significant determinant of rMSSD (β = 0.20) and HRR (β = 0.13), as did MVPA with HRR (β = 0.15). The final models explained 23% and 21% of variation in rMSSD and HRR in men, and 10% and 12% in women, respectively. Conclusions CRF was a more important determinant of cardiac autonomic function than MVPA and body fat. Furthermore, MVPA but not body fat was independently associated with cardiac autonomic function in both men and women.
Related Links	http://jultika.oulu.fi/files/nbnfi-fe2019050915026.pdf
Ending Page	2468
Page Count	10
Starting Page	2459
ISSN	01959131
e-ISSN	15300315
DOI	10.1249/mss.0000000000001387
Journal	Medicine & Science In Sports & Exercise
Issue Number	12
Volume Number	49
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	2017-12-01
Access Restriction	Open
Subject Keyword	Journal: Medicine & Science In Sports & Exercise Nutrition and Dietetics Autonomic Function
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation Sports Science