NDLI: P3-030: Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models

Content Provider	Scilit
Author	Lu, Bo
Copyright Year	2007
Description	Journal: Journal of Thoracic Oncology Poly(ADP-ribose) polymerase-1 (PARP-1) is the founding member of a family of enzymes that catalyze the addition of ADP-ribose units to proteins that mediate DNA repair pathways. Ionizing radiation induces DNA strand breaks, suggesting that PARP-1 inhibition may sensitize tumor cells to radiation.
Related Links	https://core.ac.uk/download/pdf/81978987.pdf http://www.jto.org/article/S1556086415345032/pdf
Ending Page	S620
Page Count	2
Starting Page	S619
e-ISSN	15561380
DOI	10.1097/01.jto.0000283787.20114.86
Journal	Journal of Thoracic Oncology
Issue Number	8
Volume Number	2
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	2007-08-01
Access Restriction	Open
Subject Keyword	Journal: Journal of Thoracic Oncology Research and Experimental Medicine Dna Repair Lung Cancer Cancer Models Enhances Cell Polymerase Enhances Adp Ribose
Content Type	Text
Resource Type	Article

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P3-030: Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models