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IgG kappa monoclonal gammopathy of undetermined significance presenting as acquired type III Von Willebrand syndrome
| Content Provider | Scilit |
|---|---|
| Author | Howard, Christin R. Lin, Tara L. Cunningham, Mark T. Lipe, Brea C. |
| Copyright Year | 2014 |
| Description | Journal: Blood Coagulation & Fibrinolysis Acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder associated with hematoproliferative disorders, autoimmune conditions, neoplasia and cardiovascular disorders that often present a diagnostic challenge. Monoclonal gammopathy of undetermined significance (MGUS) is one of the most common causes of AVWS that typically presents later in life with mucocutaneous or postsurgical bleeding and multimers consistent with type I or II von Willebrand disease (VWD). Here, we present the case of a patient with a 32-year history of type III VWD that was ultimately found to be AVWS related to an IgG MGUS. In this case report, we highlight the diagnostic challenges of AVWS to ensure proper identification and potentially lifesaving treatment of this rare disorder. |
| Related Links | http://europepmc.org/articles/pmc4119490?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119490/pdf |
| Ending Page | 633 |
| Page Count | 3 |
| Starting Page | 631 |
| ISSN | 09575235 |
| e-ISSN | 14735733 |
| DOI | 10.1097/mbc.0000000000000112 |
| Journal | Blood Coagulation & Fibrinolysis |
| Issue Number | 6 |
| Volume Number | 25 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2014-09-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Blood Coagulation & Fibrinolysis Acquired Bleeding Disorders, Monoclonal Gammopathy of Undetermined Significance, Von Willebrand Disease |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology |
