NDLI: Issues, indications, and controversies regarding intratympanic steroid perfusion

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Issues, indications, and controversies regarding intratympanic steroid perfusion

Content Provider	Scilit
Author	Hamid, Mohamed Trune, Dennis
Copyright Year	2008
Description	Journal: Current opinion in otolaryngology & head and neck surgery Purpose of review Office-based intratympanic inner ear steroid perfusion (ITPs) treatment for Ménière's disease, autoimmune inner ear disease, and sudden sensorineural hearing loss has been expanding over the past 10–15 years, yet remains controversial. The purpose of this review is to examine the current literature of basic science and human studies of ITPs treatment. Recent findings Animal studies exist regarding the delivery, distribution, biochemical, and microbiological changes in the inner ear post ITPs. However, few clinical studies exist on ITPs treatment in sudden sensorineural hearing loss and even less in treating Ménière's disease. There are no consistent studies regarding drug delivery methods, type, and concentration of steroids. Moreover, there are no studies comparing ITPs results to the natural history of Ménière's disease. Summary ITPs has impacted otology and neurotology practice due to increased utilization. A sound understanding of the basic science and clinical studies is needed to establish long-term efficacy of ITPs in controlling hearing loss in Ménière's disease by comparison to its natural history, as well as, potential application to other disorders.
Related Links	http://europepmc.org/articles/pmc2664082?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664082/pdf
Ending Page	440
Page Count	7
Starting Page	434
ISSN	10689508
e-ISSN	15316998
DOI	10.1097/moo.0b013e32830ce796
Journal	Current opinion in otolaryngology & head and neck surgery
Issue Number	5
Volume Number	16
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	2008-10-01
Access Restriction	Open
Subject Keyword	Journal: Current opinion in otolaryngology & head and neck surgery Audiology and Language Otorhinolaryngology Dexamethasone Perfusion, Intratympanic Perfusion, M\u00e9ni\u00e8re\'s Disease, Sudden Sensorineural Hearing Loss
Content Type	Text
Resource Type	Article
Subject	Otorhinolaryngology Surgery

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