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Failure of Enflurane and Halothane Anesthesia to Inhibit Lymphocyte Transformation in Volunteers
| Content Provider | Scilit |
|---|---|
| Author | Duncan, Peter G. Cullen, Bruce F. Calverly, Rod Smith, N. Ty Eger, Edmond I. Bone, Robert |
| Copyright Year | 1976 |
| Description | Journal: Anesthesiology Changes in the peripheral blood leukocyte count and in the ability of lymphocytes to transform in response to phytohemagglutinin were studied in healthy volunteers undergoing prolonged enflurane or halothane anesthesia without coincident surgical operation. Anesthesia was associated with a modest leukocytosis that persisted into the first post-anesthesic day, primarily due to an influx of neutrophils into the circulation. There was no significant alteration, either during or following anesthesia, in the ability of the volunteers' lymphocytes to transform in response to phytohemagglutinin when compared with either preanesthetic values or unanesthetized controls. Depression of lymphocyte transformation does not appear to follow prolonged enflurane or halothane anesthesia in the absence of a surgical procedure. |
| Related Links | https://pubs.asahq.org/anesthesiology/article-pdf/45/6/661/297130/0000542-197612000-00015.pdf |
| Ending Page | 665 |
| Page Count | 5 |
| Starting Page | 661 |
| ISSN | 00033022 |
| e-ISSN | 15281175 |
| DOI | 10.1097/00000542-197612000-00015 |
| Journal | Anesthesiology |
| Issue Number | 6 |
| Volume Number | 45 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 1976-12-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Anesthesiology Halothane Anesthesia Enflurane Or Halothane Lymphocytes To Transform Prolonged Enflurane Phytohemagglutinin |
| Content Type | Text |
| Resource Type | Synopsis |
| Subject | Anesthesiology and Pain Medicine |
