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DETECTION OF CLINICALLY UNSUSPECTED RETINAL NEOVASCULARIZATION WITH WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
| Content Provider | Scilit |
|---|---|
| Author | You, Qi Sheng Guo, Yukun Wang, Jie Wei, Xiang Camino, Acner Zang, Pengxiao Flaxel, Christina J. Bailey, Steven T. Huang, David Jia, Yali Hwang, Thomas S. |
| Copyright Year | 2020 |
| Description | Journal: Retina Purpose: To evaluate wide-field optical coherence tomography angiography (OCTA) for detection of clinically unsuspected neovascularization (NV) in diabetic retinopathy (DR). Methods: This prospective observational single-center study included adult patients with a clinical diagnosis of nonproliferative DR. Participants underwent a clinical examination, standard 7-field color photography, and OCTA with commercial and prototype swept-source devices. The wide-field OCTA was achieved by montaging five 6 × 10-mm scans from a prototype device into a 25 × 10-mm image and three 6 × 6-mm scans from a commercial device into a 15 × 6-mm image. A masked grader determined the retinopathy severity from color photographs. Two trained readers examined conventional and wide-field OCTA images for the presence of NV. Results: Of 27 participants, photographic grading found 13 mild, 7 moderate, and 7 severe nonproliferative DR. Conventional 6 × 6-mm OCTA detected NV in 2 eyes (7%) and none with 3 × 3-mm scans. Both prototype and commercial wide-field OCTA detected NV in two additional eyes. The mean area of NV was 0.38 mm2 (range 0.17–0.54 mm2). All eyes with OCTA-detected NV were photographically graded as severe nonproliferative DR. Conclusion: Wide-field OCTA can detect small NV not seen on clinical examination or color photographs and may improve the clinical evaluation of DR. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722037/pdf |
| Ending Page | 897 |
| Page Count | 7 |
| Starting Page | 891 |
| ISSN | 0275004X |
| e-ISSN | 15392864 |
| DOI | 10.1097/iae.0000000000002487 |
| Journal | Retina |
| Issue Number | 5 |
| Volume Number | 40 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2020-05-01 |
| Access Restriction | Open |
| Subject Keyword | Anti–vascular Endothelial Growth Factor Diabetic Retinopathy Optical Coherence Tomography Angiography |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
