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Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women
| Content Provider | Scilit |
|---|---|
| Author | Kiefer, Amy Lin, Jue Blackburn, Elizabeth Epel, Elissa |
| Copyright Year | 2008 |
| Description | Journal: Psychosomatic Medicine Background: Leukocyte telomere shortening can serve as a biomarker of aging, as telomere length (TL) can decline with age and shortening is positively associated with morbidity and mortality. It is therefore important to identify psychological and behavioral factors linked to accelerated telomere shortening. Stress and poorer metabolic health (greater adiposity, insulin resistance, and cortisol) correlate with shorter telomeres. Self-reported dietary restraint (DR), defined as chronic preoccupation with weight and attempts at restricting food intake, is linked to greater perceived stress, cortisol, and weight gain, when assessed in community studies (versus in weight loss programs). Objective: To test for an association between DR and TL in healthy women across a range of ages. Methods: We examined whether DR is linked to TL in two samples, one of premenopausal women (aged 20–50 years;N = 36) and one of postmenopausal women (aged 53–69 years; N = 20). Results: In both samples, higher levels of DR were associated with shorter leukocyte TL, independent of body mass index, smoking, and age. Conclusions: Chronic DR, as assessed by self-report (i.e. not caloric restriction), may be a risk factor for premature telomere shortening. Potential mechanisms are discussed. DR = dietary restraint; BMI = body mass index; TL = telomere length; DEBQ = Dutch Eating Behavior Questionnaire. |
| Related Links | http://europepmc.org/articles/pmc3078526?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078526/pdf |
| Ending Page | 849 |
| Page Count | 5 |
| Starting Page | 845 |
| ISSN | 00333174 |
| e-ISSN | 15347796 |
| DOI | 10.1097/psy.0b013e318187d05e |
| Journal | Psychosomatic Medicine |
| Issue Number | 8 |
| Volume Number | 70 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2008-10-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Psychosomatic Medicine Nutrition and Dietetics Telomere Length Dietary Restraint |
| Content Type | Text |
| Resource Type | Article |
| Subject | Developmental and Educational Psychology Applied Psychology Psychiatry and Mental Health |
