NDLI: Neural Correlates of Stress and Abdominal Obesity in Patients With Coronary Artery Disease

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Neural Correlates of Stress and Abdominal Obesity in Patients With Coronary Artery Disease

Content Provider	Scilit
Author	Moazzami, Kasra Wittbrodt, Matthew Lima, Bruno B. Levantsevych, Oleksiy Kaseer, Belal Martini, Afif Haffar, Ammer Nye, Jonathon A. Quyyumi, Arshed A. Shah, Amit Vaccarino, Viola Bremner, J. Douglas
Copyright Year	2020
Description	Journal: Psychosomatic Medicine Objective This study aimed to investigate the relationship between waist circumference as a measure of abdominal obesity and brain responses to stress among patients with coronary artery disease (CAD). Methods Patients with CAD (N = 151) underwent acute mental stress tasks in conjunction with high-resolution positron emission tomography and radiolabeled water imaging of the brain. Brain responses to mental stress were correlated with waist circumference. Results Waist circumference was positively correlated with increased activation in the right and left frontal lobes (β values ranging from 2.81 to 3.75 in the paracentral, medial, and superior gyri), left temporal lobe, left hippocampal, left amygdala, left uncus, and left anterior and posterior cingulate gyri (β values ranging from 2.93 to 3.55). Waist circumference was also negatively associated with the left and right parietal lobes, right superior temporal gyrus, and right insula and precuneus (β values ranging from 2.82 to 5.20). Conclusion Increased brain activation in the brain regions involved in the stress response and autonomic regulation of the cardiovascular system during psychological stress may underlie stress-induced overeating and abdominal obesity in patients with CAD.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138710/pdf
Ending Page	280
Page Count	9
Starting Page	272
ISSN	00333174
e-ISSN	15347796
DOI	10.1097/psy.0000000000000776
Journal	Psychosomatic Medicine
Issue Number	3
Volume Number	82
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	2020-04-01
Access Restriction	Open
Subject Keyword	Journal: Psychosomatic Medicine Endocrinology and Metabolism Coronary Artery Disease Mental Stress Body Mass Index Waist Circumference
Content Type	Text
Resource Type	Article
Subject	Developmental and Educational Psychology Applied Psychology Psychiatry and Mental Health

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