Loading...
Please wait, while we are loading the content...
Similar Documents
Early Microbe Contact and Obesity Risk
| Content Provider | Scilit |
|---|---|
| Author | Isolauri, Erika Salminen, Seppo Rautava, Samuli |
| Copyright Year | 2016 |
| Description | Journal: Journal of pediatric gastroenterology and nutrition To investigate the efficacy and safety of pre-, pro- and synbiotics in the treatment of pediatric functional constipation (FC). A recent study reported that the gut microbiota in obese children with FC differs from that of obese children without FC. The gut microbiota may be involved in the pathophysiology of FC. Pre- and probiotics have been suggested as potential treatment modalities for FC in children. PubMed and Cochrane databases were searched from inception to February 2016. We found 6 RCTs on prebiotics, 6 RCTs on probiotics and 1 RCT concerning synbiotics. Overall, most studies were at high risk of bias. The majority of studies were unable to demonstrate a significant effect of pre-, pro- or synbiotics on predefined outcome measures such as defecation frequency, fecal incontinence and painful or difficult defecation. Pre-, pro- and synbiotics were not associated with significant adverse effects. In conclusion, there is insufficient evidence to recommend pre-, pro- or synbiotics in the treatment of children with functional constipation. High-quality randomized controlled trials are warranted to further explore these treatment modalitie |
| Related Links | https://epub.ub.uni-muenchen.de/35643/1/Koletzko_B_Childhood_obesity_current_situation_2016.pdf |
| Ending Page | S5 |
| Page Count | 3 |
| Starting Page | S3 |
| ISSN | 02772116 |
| e-ISSN | 15364801 |
| DOI | 10.1097/mpg.0000000000001220 |
| Journal | Journal of pediatric gastroenterology and nutrition |
| Issue Number | 1 |
| Volume Number | 63 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2016-07-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of pediatric gastroenterology and nutrition Pediatrics and Child Health |
| Content Type | Text |
| Resource Type | Article |
| Subject | Gastroenterology Pediatrics, Perinatology and Child Health |
