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Differentiating Autoimmune Pancreatitis From Pancreatic Adenocarcinoma Using Dual-Phase Computed Tomography
| Content Provider | Scilit |
|---|---|
| Author | Zaheer, Atif Singh, Vikesh K. Akshintala, Venkata S. Kawamoto, Satomi Tsai, Salina D. Gage, Kenneth L. Fishman, Elliot K. |
| Copyright Year | 2014 |
| Description | Journal: Journal of computer assisted tomography To study features on dual phase CT that help differentiate autoimmune pancreatitis (AIP) from pancreatic adenocarcinoma (PA). The CTs of 32 patients with AIP were matched with equal number of PA and independently evaluated by 3 radiologists who assigned a diagnosis of AIP, PA, or unsure. Interobserver agreement between radiologists was evaluated using kappa statistics. The mean accuracy for diagnosing AIP and PA was 68% and 83%, respectively. There was moderate agreement between radiologists (κ: 0.58, p<0.0001). The most common findings for AIP: CBD stricture (63%), bile duct wall hyperenhancement (47%), and diffuse parenchymal enlargement (41%). The most common findings for PA: Focal mass (78%, κ: 0.58, p<0.0001) and pancreatic ductal dilatation (69%, κ: 0.7, p<0.0001). Findings helpful for diagnosing AIP were diffuse enlargement, parenchymal atrophy as well as absence of pancreatic duct dilatation and focal mass. Findings helpful for diagnosing PA were focal mass and pancreatic ductal dilatation. Misdiagnosis of PA in patients with AIP was due to focal mass, pancreatic duct dilatation and pancreatic atrophy and AIP in patients with PA was due to absence of atrophy, presence of diffuse enlargement and peripancreatic halo. Diffuse enlargement, hypoenhancement and characteristic peripancreatic halo are strong indicators for a diagnosis of AIP. Radiologists demonstrated moderate agreement in distinguishing AIP from PA on the basis of CT imaging. |
| Related Links | http://europepmc.org/articles/pmc4394855?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394855/pdf |
| Ending Page | 152 |
| Page Count | 7 |
| Starting Page | 146 |
| ISSN | 03638715 |
| e-ISSN | 15323145 |
| DOI | 10.1097/rct.0b013e3182a9a431 |
| Journal | Journal of computer assisted tomography |
| Issue Number | 1 |
| Volume Number | Publish Ah |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2014-01-20 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of computer assisted tomography Radiology, Nuclear Medicine and Imaging Autoimmune Pancreatitis Pancreas Adenocarcinoma Reader Variability |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging |
