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Acute Effects of Ambient Particulate Matter on Blood Pressure
| Content Provider | Scilit |
|---|---|
| Author | Dvonch, J. Timothy Kannan, Srimathi Schulz, Amy J. Keeler, Gerald J. Mentz, Graciela Benjamin, Alison Max, Paul Bard, Robert L. Brook, Robert D. |
| Copyright Year | 2009 |
| Description | Journal: Hypertension Recent studies have suggested a link between exposure to ambient particulate matter <2.5 μm in diameter (PM$ _{2.5}$ ) and adverse cardiovascular outcomes. The objective of this study was to examine the effects of differing community-level exposure to PM$ _{2.5}$ on daily measures of blood pressure (BP) among an adult population. During the period May 2002 through April 2003, BP was examined at 2 time points for 347 adults residing in 3 distinct communities of Detroit, Michigan. Exposure to PM$ _{2.5}$ was assessed in each community during this period, along with multivariate associations between PM$ _{2.5}$ and BP. In models combining all 3 of the communities, PM$ _{2.5}$ was significantly associated with systolic blood pressure; a 10-μg/m$ ^{3}$ increase in daily PM$ _{2.5}$ was associated with a 3.2-mm Hg increase in systolic blood pressure ( P =0.05). However, in models that added a location interaction, larger effects were observed for systolic blood pressure within the community with highest PM$ _{2.5}$ levels; a 10-μg/m$ ^{3}$ increase in daily PM$ _{2.5}$ was associated with a 8.6-mm Hg increase in systolic blood pressure ( P =0.01). We also found young age (<55 years) and not taking BP medications to be significant predictors of increased BP effects. Among those taking BP medications, the PM$ _{2.5}$ effect on BP appeared to be mitigated, partially explaining the age effect, because those participants <55 years of age were less likely to take BP medications. Short-term increases in exposure to ambient PM$ _{2.5}$ are associated with acute increases in BP in adults, especially within communities with elevated levels of exposure. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593813/pdf https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.108.123877 |
| Ending Page | 859 |
| Page Count | 7 |
| Starting Page | 853 |
| ISSN | 0194911X |
| e-ISSN | 15244563 |
| DOI | 10.1161/hypertensionaha.108.123877 |
| Journal | Hypertension |
| Issue Number | 5 |
| Volume Number | 53 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2009-05-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Hypertension Peripheral Vascular Disease Particulate Matter Cardiovascular Outcomes Blood Pressure Air Pollution |
| Content Type | Text |
| Resource Type | Article |
| Subject | Internal Medicine |
