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Neurogenesis of Excitation-Contraction Uncoupling in Aging Skeletal Muscle
| Content Provider | Scilit |
|---|---|
| Author | Payne, Anthony Michael Delbono, Osvaldo |
| Copyright Year | 2004 |
| Description | Journal: Exercise and sport sciences reviews PAYNE, A. M., and O. DELBONO. Neurogenesis of excitation-contraction uncoupling in aging skeletal muscle. Exerc. Sport Sci. Rev., Vol. 32, No. 1, pp. 36–40, 2004. Excitation-contraction (EC) uncoupling is a major cause of decreased muscle force generating capacity (specific force). However, the underlying mechanisms of EC uncoupling in muscle from aging mammals have not been characterized. We propose that impaired motor neuron function with aging leading to muscle denervation, a process probably initiated earlier than detected by in vitro morphologic techniques, results in EC uncoupling. |
| Related Links | http://pdfs.journals.lww.com/acsm-essr/2004/01000/Neurogenesis_of_Excitation_Contraction_Uncoupling.8.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1503219852284;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21Csk0OpQi3YbjEMdSoz2UhVybFqQxA7lKwSUlA502zQZr96TQRwhVlocEp/sJ586aVbcBFlltKNKo+tbuMfL73hiPqJliudqs17cHeLcLbV/CqjlP3IO0jGHlHQtJWcICDdAyGJMnpi6RlbEJaRheGeh5z5uvqz3FLHgPKVXJzdDveR1/6q+GFE7AtZdx5OrPBxhi9s92HHB7di/aE0++c=;hash|r8V41tMS83/vQN188EQusg== |
| Ending Page | 40 |
| Page Count | 5 |
| Starting Page | 36 |
| ISSN | 00916331 |
| e-ISSN | 15383008 |
| DOI | 10.1097/00003677-200401000-00008 |
| Journal | Exercise and sport sciences reviews |
| Issue Number | 1 |
| Volume Number | 32 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2004-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Exercise and sport sciences reviews Excitation Contraction |
| Content Type | Text |
| Resource Type | Article |
| Subject | Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation Sports Science |