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Advances in Rift Valley fever research: insights for disease prevention

Content Provider	Scilit
Author	LaBeaud, A. Desiree Kazura, James W. King, Charles
Copyright Year	2010
Description	Journal: Current Opinion in Infectious Diseases Purpose of review The purpose was to review recent research on Rift Valley fever virus (RVFV) infection, encompassing four main areas: epidemiology and outbreak prediction, viral pathogenesis, human diagnostics and therapeutics, and vaccine and therapeutic candidates. Recent findings RVFV continues to extend its range in Africa and the Middle East. Better definition of RVFV-related clinical syndromes and human risk factors for severe disease, combined with early-warning systems based on remote-sensing, simplified rapid diagnostics, and tele-epidemiology, hold promise for earlier deployment of effective outbreak control measures. Advances in understanding of viral replication pathways and host cell-related pathogenesis suggest means for antiviral therapeutics and for more effective vaccination strategies based on genetically engineered virus strains or subunit vaccines. Summary RVFV is a significant health and economic burden in many areas of Africa, and remains a serious threat to other parts of the world. Development of more effective methods for RVFV outbreak prevention and control remains a global health priority.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126654/pdf
Ending Page	408
Page Count	6
Starting Page	403
ISSN	09517375
e-ISSN	14736527
DOI	10.1097/qco.0b013e32833c3da6
Journal	Current Opinion in Infectious Diseases
Issue Number	5
Volume Number	23
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publisher Date	2010-10-01
Access Restriction	Open
Subject Keyword	Journal: Current Opinion in Infectious Diseases Infectious Diseases Arbovirus Infections Hemorrhagic Fevers Rift Valley Fever Rift Valley Fever Virus
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Microbiology (medical)

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