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One Bout of Exercise Alters Free-Living Postprandial Glycemia in Type 2 Diabetes
| Content Provider | Scilit |
|---|---|
| Author | Oberlin, Douglas J. Mikus, Catherine R. Kearney, Monica L. Hinton, Pamela Manrique, Camila Leidy, Heather J. Kanaley, Jill A. Rector, R. Scott Thyfault, John P. |
| Copyright Year | 2014 |
| Description | Journal: Medicine & Science In Sports & Exercise Purpose Elevated postprandial glycemic (PPG) excursions are significant risk factors for cardiovascular disease in type 2 diabetes patients. In this study, we tested if and for how many meals a single bout of exercise would reduce PPG responses to subsequent meals in type 2 diabetes (T2D) patients using a continuous glucose monitor system (CGMS). Methods We recruited nine sedentary (<30 min·wk−1 of exercise) individuals with T2D (mean ± SD; body mass index = 36.0 ± 1.1 kg·m−2, age = 60.3 ± 1.0 yr, HbA1c = 6.3% ± 0.2%). The subjects consumed a eucaloric diet (51% carbohydrate, 31% fat, and 18% protein) consisting of three meals, identical in composition, for a 2-d period while wearing a continuous glucose monitor system in two different conditions (exercise [EX], one 60-min bout at 60%–75% of heart rate reserve performed before breakfast), vs a sedentary [SED] condition). We quantified 24-h average glucose, PPG area under the curve (AUC; 4-h glucose AUC after meals), and PPG-2 h (2 h postprandial glucose). Results EX significantly reduced average [glucose] during the first 24-h period (P = 0.03). EX caused a reduction in PPG-AUC (P = 0.02) for all of the meals during the 2 d (main effect between conditions). A comparison between the EX and the SED conditions at each meal revealed that EX reduced PPG-AUC after the second meal of day 1 (lunch) (P = 0.04). PPG-2 h was not significantly different between EX and SED. Conclusions Although a single EX bout does lower 24-h average [glucose], it only significantly lowered PPG-AUC at the second meal after the bout, suggesting that daily exercise may be needed to most effectively improve PPG at the advent of exercise training in T2D patients. |
| Related Links | http://europepmc.org/articles/pmc4521618?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521618/pdf |
| Ending Page | 238 |
| Page Count | 7 |
| Starting Page | 232 |
| ISSN | 01959131 |
| e-ISSN | 15300315 |
| DOI | 10.1249/mss.0b013e3182a54d85 |
| Journal | Medicine & Science In Sports & Exercise |
| Issue Number | 2 |
| Volume Number | 46 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2014-02-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Medicine & Science In Sports & Exercise Endocrinology and Metabolism Nutrition and Dietetics Post-prandial Glucose Glycemic Control Type 2 Diabetes Continuous Glucose Monitoring |
| Content Type | Text |
| Resource Type | Article |
| Subject | Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation Sports Science |
