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Prevalence of a Gluten-free Diet and Improvement of Clinical Symptoms in Patients with Inflammatory Bowel Diseases
| Content Provider | Scilit |
|---|---|
| Author | Herfarth, Hans H. Martin, Christopher F. Sandler, Robert S. Kappelman, Michael D. Long, Millie D. |
| Copyright Year | 2014 |
| Description | Journal: Inflammatory Bowel Diseases Maintaining a gluten-free diet (GFD) without an underlying diagnosis of celiac disease has enjoyed widespread acceptance in the Unites States. We performed a cross-sectional study using a GFD questionnaire in 1647 patients with inflammatory bowel diseases (IBD) participating in the CCFA Partners longitudinal Internet-based cohort. A diagnosis of celiac disease and non-celiac gluten sensitivity were reported by 10 (0.6%) and 81 (4.9%) respondents, respectively. Three hundred fourteen (19.1%) participants reported having previously tried a GFD and 135 (8.2%) reported current use of GFD. Overall 65.6% of all patients, who attempted a GFD, described an improvement of their gastrointestinal symptoms and 38.3% reported fewer or less severe IBD flares. In patients currently attempting a GFD, excellent adherence was associated with significant improvement of fatigue (P < 0.03). In this large group of patients with IBD, a substantial number had attempted a GFD, of whom the majority had some form of improvement in gastrointestinal symptoms. Testing a GFD in clinical practice in patients with significant intestinal symptoms, which are not solely explained by the degree of intestinal inflammation, has the potential to be a safe and highly efficient therapeutic approach. Further prospective studies into mechanisms of gluten sensitivity in IBD are warranted. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331053/pdf https://academic.oup.com/ibdjournal/article-pdf/20/7/1194/23412547/ibd1194.pdf |
| Ending Page | 1197 |
| Page Count | 4 |
| Starting Page | 1194 |
| ISSN | 10780998 |
| e-ISSN | 15364844 |
| DOI | 10.1097/mib.0000000000000077 |
| Journal | Inflammatory Bowel Diseases |
| Issue Number | 7 |
| Volume Number | 20 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2014-07-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Inflammatory Bowel Diseases Gastroenterology and Hepatology Crohn's Disease Ulcerative Colitis Celiac Disease |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Allergy Gastroenterology |
