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Safety and Impact of Chlorhexidine Antisepsis Interventions for Improving Neonatal Health in Developing Countries
| Content Provider | Scilit |
|---|---|
| Author | Mullany, Luke C. Darmstadt, Gary L. Tielsch, James |
| Copyright Year | 2006 |
| Description | Journal: The Pediatric infectious disease journal Affordable, efficacious, and safe interventions to prevent infections and improve neonatal survival in low-resource settings are needed. Chlorhexidine is a broad-spectrum antiseptic that has been used extensively for many decades in hospital and other clinical settings. It has also been given as maternal vaginal lavage, full-body newborn skin cleansing, and/or umbilical cord cleansing to prevent infection in neonates. Recent evidence suggests that these chlorhexidine interventions may have significant public health impact on the burden of neonatal infection and mortality in developing countries. This review examines the available data from randomized and nonrandomized studies of chlorhexidine cleansing, with a primary focus on potential uses in low-resource settings. Safety issues related to chlorhexidine use in newborns are reviewed, and future research priorities for chlorhexidine interventions for neonatal health in developing countries are discussed. |
| Related Links | http://europepmc.org/articles/pmc2386993?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386993/pdf |
| Ending Page | 675 |
| Page Count | 11 |
| Starting Page | 665 |
| ISSN | 08913668 |
| e-ISSN | 15320987 |
| DOI | 10.1097/01.inf.0000223489.02791.70 |
| Journal | The Pediatric infectious disease journal |
| Issue Number | 8 |
| Volume Number | 25 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2006-08-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: The Pediatric infectious disease journal Infectious Diseases Superficial Infection |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Pediatrics, Perinatology and Child Health Microbiology (medical) |
