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Development and Testing of an Integrated Score for Physical Behaviors
| Content Provider | Scilit |
|---|---|
| Author | Keadle, Sarah Kozey Kravitz, Eli S. Matthews, Charles E. Tseng, Marilyn Carroll, Raymond J. |
| Copyright Year | 2019 |
| Description | Journal: Medicine & Science In Sports & Exercise Purpose Interest in a variety of physical behaviors (e.g., exercise, sitting time, sleep) in relation to health outcomes creates a need for new statistical approaches to analyze the joint effects of these distinct but inter-related physical behaviors. We developed and tested an integrated physical behavior score (PBS). Methods National Institutes of Health-American Association of Retired Persons Diet and Health Study participants (N = 163,016) completed a questionnaire (2004–2006) asking about time spent in five exercise and nonexercise physical activities, two sedentary behaviors (television and nontelevision), and sleep. In half of the sample, we used shape-constrained additive regression to model the relationship between each behavior and survival. Maximum logit scores from each of the eight behavior-survival functions were summed to produce a PBS that was proportionally rescaled to range from 0 to 100. We examined predictive validity of the PBS in the other half-sample using Cox Proportional Hazards models after adjustment for covariates for all-cause and cause-specific mortality. Results In the testing sample, over an average of 6.6 yr of follow-up, 8732 deaths occurred. We found a strong graded decline in risk of all-cause mortality across quintiles of PBS (Q5 vs Q1 hazard ratio [95% CI] = 0.53 [0.49, 0.57]). Risk estimates for the PBS were higher than any of the components in isolation. Results were similar but stronger for cardiovascular disease (Q5 vs Q1 = 0.42 [0.39, 0.48]) and other mortality (Q5 vs Q1 = 0.42 [0.36, 0.48]). The relationship between PBS and mortality was observed in stratified analyses by median age, sex, body mass index, and health status. Conclusions We developed a novel statistical method generated a composite physical behavior that is predictive of mortality outcomes. Future research is needed to test this approach in an independent sample. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629509/pdf |
| Ending Page | 1766 |
| Page Count | 8 |
| Starting Page | 1759 |
| ISSN | 01959131 |
| e-ISSN | 15300315 |
| DOI | 10.1249/mss.0000000000001955 |
| Journal | Medicine & Science In Sports & Exercise |
| Issue Number | 8 |
| Volume Number | 51 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2019-08-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Medicine & Science In Sports & Exercise Sport Sciences Physical Activity Sedentary Behavior Prospective Cohort |
| Content Type | Text |
| Resource Type | Article |
| Subject | Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation Sports Science |
