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Correlation Between PaO2/FIO2 and Peripheral Capillary Oxygenation/FIO2 in Burned Children With Smoke Inhalation Injury
| Content Provider | Scilit |
|---|---|
| Author | Cambiaso-Daniel, Janos Voigt, Charles D. Rivas, Eric Hundeshagen, Gabriel Lopez, Omar Nunez Kamolz, Lars-Peter Sljivich, Michaela Sousse, Linda E. Herndon, David N. Suman, Oscar E. Kinsky, Michael P. Mlcak, Ronald P. |
| Copyright Year | 2017 |
| Description | Journal: Pediatric Critical Care Medicine |
| Abstract | Objectives: Determine whether the peripheral capillary oxygenation/Fio2 ratio correlates with the Pao2/Fio2 ratio in burned children with smoke inhalation injury, with the goal of understanding if the peripheral capillary oxygenation/Fio2 ratio can serve as a surrogate for the Pao2/Fio2 ratio for the diagnosis of acute respiratory distress syndrome. Design: Retrospective chart review. Setting: Shriners Hospitals for Children—Galveston. Patients: All burned children with smoke inhalation injury who were admitted from 1996 to 2014 and had simultaneously obtained peripheral capillary oxygenation, Fio2 and Pao2 measurements. Interventions: None. Measurements and Main Results: Two hundred seventy-three patients (63% male, 8 ± 5 yr, 53% ± 24% total body surface area burns) were analyzed. Peripheral capillary oxygenation/Fio2 ratios were divided into four subgroups based on peripheral capillary oxygenation values (≤ 100%, ≤ 98%, ≤ 95%, and ≤ 92%). Significance was accepted at r2 greater than 0.81. The r2 (number of matches) was 0.66 (23,072) for less than or equal to 100%, 0.87 (18,932) for less than or equal to 98%, 0.89 (7,056) for less than or equal to 95%, and 0.93 (4,229) for less than or equal to 92%. In the subgroup of patients who developed acute respiratory distress syndrome, r2 was 0.65 (8,357) for less than or equal to 100%, 0.89 (7,578) for less than or equal to 98%, 0.89 (4,115) for less than or equal to 95%, and 0.91 (2,288) less than or equal to 92%. Conclusions: Pao2/Fio2 and peripheral capillary oxygenation/Fio2 strongly correlate in burned children with smoke inhalation injury, with a peripheral capillary oxygenation of less than 92% providing the strongest correlation. Thus, peripheral capillary oxygenation/Fio2 ratio may be able to serve as surrogate for Pao2/Fio2, especially when titrating Fio2 to achieve a peripheral capillary oxygenation of 90–95% (i.e., in the acute respiratory distress syndrome range). |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628154/pdf |
| Ending Page | e476 |
| Page Count | 5 |
| Starting Page | e472 |
| ISSN | 15297535 |
| DOI | 10.1097/pcc.0000000000001287 |
| Journal | Pediatric Critical Care Medicine |
| Issue Number | 10 |
| Volume Number | 18 |
| Language | English |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Publisher Date | 2017-10-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Pediatric Critical Care Medicine Sport Sciences Acute Lung Injury Acute Respiratory Distress Syndrome Critical Care Pediatric Acute Lung Injury Consensus Conference |
| Content Type | Text |
| Resource Type | Article |
| Subject | Critical Care and Intensive Care Medicine Pediatrics, Perinatology and Child Health |
