NDLI: Difficulties in the antenatal assessment of neonatal alloimmune thrombocytopenia

Content Provider	Scilit
Author	Marzusch, Klaus Fischer, Juergen Dietl, Johannes Wiest, Elfriede Völklein, Karl Schnaidt, Martina
Copyright Year	1993
Description	Journal: Acta Obstetricia et Gynecologica Scandinavica In this paper we present a patient with an initially questionable history of neonatal alloimmune thrombocytopenia (NAT) due to materno-fetal HPA-la $(PL^{Al}$) incompatibility. No circulating antibodies were detectable in untreated maternal serum, but an adsorption/elution technique enabled the demonstration of the platelet-specific anti-HPA-la $(anti-PL^{Al}$) in maternal serum. Cordocentesis at 35 weeks of gestation revealed a fetal platelet count of 18 × $10^{9}$/1. Intrauterine platelet transfusion with HPA-Ia $(PL^{Al}$)-negative donor platelets was performed prior to cesarean section.
Ending Page	585
Starting Page	583
ISSN	00221295
e-ISSN	16000412
DOI	10.3109/00016349309058169
Journal	Acta Obstetricia et Gynecologica Scandinavica
Issue Number	7
Volume Number	72
Language	English
Publisher	Wiley-Blackwell
Publisher Date	1993-01-01
Access Restriction	Open
Subject Keyword	Journal: Acta Obstetricia et Gynecologica Scandinavica Obstetrics and Gynecology
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology

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