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Mycobacterial infections in solid organ transplant recipients
| Content Provider | Scilit |
|---|---|
| Author | Meije, Y. Piersimoni, C. Torre-Cisneros, J. Dilektasli, A. G. Aguado, J. M. |
| Copyright Year | 2014 |
| Description | Journal: Clinical Microbiology and Infection Mycobacterial infections represent a growing challenge for solid organ transplant recipients (SOT). The adverse effects of tuberculosis (TB) therapy present a major difficulty, due to the interactions with immunosuppressive drugs and direct drug toxicity. While TB may be donor-transmitted or community-acquired, it usually develops at a latent infection site in the recipient. Pre-transplant prevention efforts will improve transplant outcomes and avoid the complications associated with post-transplant diagnosis and treatment. The present review and consensus manuscript is based on the updated published information and expert recommendations. The current data about epidemiology, diagnosis, new regimens for the treatment of latent TB infection (LTBI), the experience with rifamycins for the treatment of active TB in the post-transplant period and the experience with isoniazid for LTBI in the liver transplant population, are also reviewed. We attempt to provide useful recommendations for each transplant period and problem concerning mycobacterial infections in SOT recipients |
| Ending Page | 101 |
| Starting Page | 89 |
| ISSN | 2573508X |
| e-ISSN | 14690691 |
| DOI | 10.1111/1469-0691.12641 |
| Journal | Clinical Microbiology and Infection |
| Issue Number | s7 |
| Volume Number | 20 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2014-09-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Clinical Microbiology and Infection Gastroenterology and Hepatology Latent Tuberculosis Infection Nonātuberculous Mycobacteria Solid Organ Transplantation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Microbiology (medical) |