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Effects of long-term contact lens wear on the corneal endothelium
| Content Provider | Scilit |
|---|---|
| Author | Setälä, Kirsi Vasara, Kristiina Vesti, Eija Ruusuvaara, Pekka |
| Copyright Year | 1998 |
| Description | Journal: Acta ophthalmologica Scandinavica To analyze the long-term effects of soft and hard (PMMA) contact lenses (CL) on the human corneal endothelium. One hundred and one contact lens wearers with > or =10 years' wearing time and 50 healthy control subjects were examined with specular microscope. The mean corneal endothelial cell densities of the CL wearers (2846 cells/mm2) and of the control eyes (2940 cells/mm2) differed by 94 cells/mm2 (p<0.05). The mean values for the coefficient of variation (CV) differed significantly (p<0.0001); for all CL wearers: mean CV=0.31, vs. for controls: 0.22. The mean endothelial cell density of the eyes exposed to CL wear for more than 25 years (30 eyes) was 2575 cells/mm2 (mean CV: 0.36). Rather low densities (<2000 cells/mm2) were observed in 16 eyes of the CL group (8%). Cell densities less than 2500 cells/mm2 were observed in a total of 41 eyes (20%) in the CL group, whereas in the control group (100 eyes) all of the subjects, except one, had cell densities of more than 2500 cells/mm2 in both eyes. A subgroup of PMMA as well as soft contact lens wearers react not only with high pleomorphism and polymegethism but also with a decrease in endothelial cell density. |
| Related Links | https://onlinelibrary.wiley.com/doi/pdf/10.1034/j.1600-0420.1998.760309.x |
| Ending Page | 303 |
| Page Count | 5 |
| Starting Page | 299 |
| ISSN | 13953907 |
| e-ISSN | 16000420 |
| DOI | 10.1034/j.1600-0420.1998.760309.x |
| Journal | Acta ophthalmologica Scandinavica |
| Issue Number | 3 |
| Volume Number | 76 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 1998-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta ophthalmologica Scandinavica Contact Lens Wearers |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
