Loading...
Please wait, while we are loading the content...
Thrombolytic agents for arterial and venous thromboses in neonates
| Content Provider | Scilit |
|---|---|
| Author | John, Cheri M. Harkensee, Christian |
| Copyright Year | 2005 |
| Description | Journal: Cochrane Database of Systematic Reviews Clinically symptomatic thromboses are infrequent but serious complications in infants undergoing intensive care. Most are related to central vascular catheters. Symptomatic thrombosis may cause severe morbidity due to irreversible organ damage and also loss of limbs. To assess the efficacy and safety of thrombolytic agents in neonatal arterial and venous thromboses. We searched the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 2, 2004), MEDLINE (January 1966 to January 2004), EMBASE (January 1980 to January 2004), and CINAHL (January 1982 to January 2004). We also contacted authors of appropriate review articles. Randomised controlled trials (RCT) and quasi RCT comparing thrombolytic agents with either heparin or observation in neonates with symptomatic neonatal arterial and venous thromboses were included. Two reviewers independently searched for eligible trials. No eligible studies were found even after contacting authors of review articles for details of any unpublished trials. No randomised controlled trials (RCT) or quasi-RCT were found. No conclusions could be made as no eligible studies were found. It is time that a randomised controlled trial was performed comparing thrombolytic therapy to heparin therapy to aid neonatologists in the treatment of arterial and venous thromboses. |
| Related Links | http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004342.pub2/pdf |
| ISSN | 1469493X |
| e-ISSN | 14651858 |
| DOI | 10.1002/14651858.cd004342.pub2 |
| Journal | Cochrane Database of Systematic Reviews |
| Issue Number | 1 |
| Volume Number | 2010 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2005-01-24 |
| Access Restriction | Open |
| Subject Keyword | Journal: Cochrane Database of Systematic Reviews Pediatrics and Child Health Venous Thromboses |
| Content Type | Text |
| Resource Type | Article |
