NDLI: Measuring psychotic depression

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Measuring psychotic depression

Content Provider	Scilit
Author	Østergaard, S. D. Meyers, B. S. Flint, A. J. Mulsant, B. H. Whyte, E. M. Ulbricht, C. M. Bech, P. Rothschild, A. J.
Copyright Year	2013
Description	Journal: Acta Psychiatrica Scandinavica Psychotic depression (PD) is a highly debilitating condition, which needs intensive monitoring. However, there is no established rating scale for evaluating the severity of PD. The aim of this analysis was to assess the psychometric properties of established depression rating scales and a number of new composite rating scales, covering both depressive and psychotic symptoms, in relation to PD. The psychometric properties of the rating scales were evaluated based on data from the Study of Pharmacotherapy of Psychotic Depression. A rating scale consisting of the 6-item Hamilton melancholia subscale (HAM-D6 ) plus five items from the Brief Psychiatric Rating Scale (BPRS), named the HAMD-BPRS11 , displayed clinical validity (Spearman's correlation coefficient between HAMD-BPRS11 and Clinical Global Impression - Severity (CGI-S) scores = 0.79-0.84), responsiveness (Spearman's correlation coefficient between change in HAMD-BPRS11 and Clinical Global Impression - Improvement (CGI-I) scores = -0.74--0.78) and unidimensionality (Loevinger's coefficient of homogeneity = 0.41) in the evaluation of PD. The HAM-D6 fulfilled the same criteria, whereas the full 17-item Hamilton Depression Scale failed to meet criteria for unidimensionality. Our results suggest that the HAMD-BPRS11 is a more valid measure than pure depression scales for evaluating the severity of PD.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819398/pdf
Ending Page	220
Page Count	10
Starting Page	211
e-ISSN	16000447
DOI	10.1111/acps.12165
Journal	Acta Psychiatrica Scandinavica
Issue Number	3
Volume Number	129
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2013-06-25
Access Restriction	Open
Subject Keyword	Journal: Acta Psychiatrica Scandinavica Psychiatry and Mental Health Affective Disorders
Content Type	Text

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