NDLI: Between- and within-site variability of fMRI localizations

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Between- and within-site variability of fMRI localizations

Content Provider	Scilit
Author	Rath, Jakob Wurnig, Moritz Fischmeister, Florian Klinger, Nicolaus Höllinger, Ilse Geißler, Alexander Aichhorn, Markus Foki, Thomas Kronbichler, Martin Nickel, Janpeter Siedentopf, Christian Staffen, Wolfgang Verius, Michael Golaszewski, Stefan Koppelstaetter, Florian Auff, Eduard Felber, Stephan Seitz, Rüdiger J. Beisteiner, Roland
Copyright Year	2016
Description	Journal: Human brain mapping This study provides first data about the spatial variability of fMRI sensorimotor localizations when investigating the same subjects at different fMRI sites. Results are comparable to a previous patient study. We found a median between-site variability of about 6 mm independent of task (motor or sensory) and experimental standardization (high or low). An intraclass correlation coefficient analysis using data quality measures indicated a major influence of the fMRI site on variability. In accordance with this, within-site localization variability was considerably lower (about 3 mm). We conclude that the fMRI site is a considerable confound for localization of brain activity. However, when performed by experienced clinical fMRI experts, brain pathology does not seem to have a relevant impact on the reliability of fMRI localizations
Ending Page	2160
Starting Page	2151
ISSN	00221295
e-ISSN	10970193
DOI	10.1002/hbm.23162
Journal	Human brain mapping
Issue Number	6
Volume Number	37
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2016-03-09
Access Restriction	Open
Subject Keyword	Journal: Human brain mapping Multicenter Study Somatosensory Cortex
Content Type	Text
Resource Type	Article
Subject	Physiology

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