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Prevalence and Correlates of Sleep-Disordered Breathing in Older Men: Osteoporotic Fractures in Men Sleep Study
| Content Provider | Scilit |
|---|---|
| Author | Mehra, Reena Stone, Katie L. Blackwell, Terri Israel, Sonia Ancoli Dam, Thuy-Tien L. Stefanick, Marcia L. Redline, Susan |
| Copyright Year | 2007 |
| Description | Journal: Journal of the American Geriatrics Society To determine the prevalence and distribution of sleep-disordered breathing and associated correlates in a large cohort of older men using several standardized definitions. Cross-sectional analyses. Six U.S. communities. Polysomnography was performed on 2,911 participants of the Outcomes of Sleep Disorders in Older Men Sleep Study (mean age+/-standard deviation 76.38+/-5.53; body mass index 27.17+/-3.8 kg/m(2)). Three outcomes were assessed: sleep-disordered breathing (respiratory disturbance index > or =15), obstructive apnea (obstructive apnea index > or =5), and central apnea (central apnea index > or =5). The prevalence of moderate-severe sleep-disordered breathing was estimated to be 21.4% to 26.4%. Multivariable logistic regression models demonstrated that age (adjusted odds ratio (AOR) per 5-year increase =1.24, 95% confidence interval (CI)=1.15-1.34), obesity (AOR=2.54, 95% CI=2.09-3.09), Asian versus Caucasian race (AOR=2.14, 95% CI=1.33-3.45), snoring (AOR=2.01, 95% CI=1.62-2.49), sleepiness (AOR=1.41, 95% CI=1.11-1.79), hypertension (AOR=1.26, 95% CI=1.06-1.50), cardiovascular disease (AOR=1.24, 95% CI=1.19-1.29), and heart failure (AOR=1.81, 1.31-2.51) were independently associated with sleep-disordered breathing; snoring (AOR=2.10, 95% CI=1.67-2.70), age (AOR per 5-year increase=1.27, 95% CI=1.18-1.38), obesity (AOR=1.48, 95% CI=1.21-1.82), and heart failure (AOR=1.60, 95% CI=1.15-2.24) were associated with obstructive apnea; and age (AOR=1.33, 1.17-1.50) and heart failure (AOR=1.88, 95% CI=1.17-3.04) were associated with central apnea. Regardless of definition, a high prevalence of sleep disorders is observed in community-dwelling older men. Qualitatively similar associations were observed between sleep disorders and snoring, obesity, and comorbidities, as reported for middle aged populations. Asian race was associated with sleep-disordered breathing. |
| Related Links | http://europepmc.org/articles/pmc2780325?pdf=render https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780325/pdf http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2007.01290.x/pdf |
| Ending Page | 1364 |
| Page Count | 9 |
| Starting Page | 1356 |
| e-ISSN | 15325415 |
| DOI | 10.1111/j.1532-5415.2007.01290.x |
| Journal | Journal of the American Geriatrics Society |
| Issue Number | 9 |
| Volume Number | 55 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2007-09-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of the American Geriatrics Society Sleep Apnea Cohort Study |
| Content Type | Text |
| Resource Type | Article |
