NDLI: Antiparasitical chemotherapy in Chagas’ disease cardiomyopathy: current evidence

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Antiparasitical chemotherapy in Chagas’ disease cardiomyopathy: current evidence

Content Provider	Scilit
Author	Guedes, Paulo Marcos Matta Gutierrez, Fredy Rs Nascimento, Manuela Do-Valle-Matta, Maria Adelaide Silva, Joao Santana
Copyright Year	2012
Description	Journal: Tropical Medicine & International Health Chronic chagasic cardiomyopathy affects 20% of Chagas disease patients. At present, Chagas disease chemotherapy uses nitrofurans, benznidazole (Rochagan (R), Rodanil (R), Roche) or nifurtimox (Lampit (R), Bayer). Treatment during acute and recent chronic phases in childhood effects 71.5% and 57.6%, respectively, of parasitological cure. However, in clinical trials during the late chronic phase, only 5.9% of parasitological cure were achieved. This review focuses on the benefit from aetiological treatment to avoid, stop or revert myocarditis. Divergent data gathered from clinical practice are not convincing to support prescription of aetiological treatment as routine for indeterminate and cardiac chronic patients
Ending Page	1065
Starting Page	1057
ISSN	2573508X
e-ISSN	13653156
DOI	10.1111/j.1365-3156.2012.03025.x
Journal	Tropical Medicine & International Health
Issue Number	9
Volume Number	17
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2012-06-12
Access Restriction	Open
Subject Keyword	Journal: Tropical Medicine & International Health Trypanosoma Cruzi Parasite Persistence Cardiac Inflammation Maladie De Chagas Persistance Du Parasite Inflammation Cardiaque Enfermedad De Chagas Persistencia Parasitológica Inflamación Cardiaca
Content Type	Text
Resource Type	Article

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