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A high-throughput eight-channel probe head for murine MRI at 9.4 T
| Content Provider | Scilit |
|---|---|
| Author | Lanz, Titus Müller, Matthias Barnes, Hannah Neubauer, Stefan Schneider, Jürgen E. |
| Copyright Year | 2010 |
| Description | Journal: Magnetic Resonance in Medicine Murine MRI studies are conducted on dedicated MR systems, typically equipped with ultra-high-field magnets (≥4.7 T; bore size: ∼12–25 cm), using a single transmit-receive coil (volume or surface coil in linear or quadrature mode) or a transmit-receive coil combination. Here, we report on the design and characterization of an eight-channel volume receive-coil array for murine MRI at 400 MHz. The array was combined with a volume-transmit coil and integrated into one probe head. Therefore, the animal handling is fully decoupled from the radiofrequency setup. Furthermore, fixed tune and match of the coils and a reduced number of connectors minimized the setup time. Optimized preamplifier design was essential for minimizing the noise coupling between the elements. A comprehensive characterization of transmit volume resonator and receive coil array is provided. The performance of the coil array is compared to a quadrature-driven birdcage coil with identical sensitive volume. It is shown that the miniature size of the elements resulted in coil noise domination and therefore reduced signal-to-noise-ratio performance in the center compared to the quadrature birdcage. However, it allowed for 3-fold accelerated imaging of mice in vivo, reducing scan time requirements and thus increasing the number of mice that can be scanned per unit of time. Magn Reson Med, 2010. © 2010 Wiley-Liss, Inc. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071940/pdf |
| Ending Page | 87 |
| Page Count | 8 |
| Starting Page | 80 |
| e-ISSN | 15222594 |
| DOI | 10.1002/mrm.22414 |
| Journal | Magnetic Resonance in Medicine |
| Issue Number | 1 |
| Volume Number | 64 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-05-17 |
| Access Restriction | Open |
| Subject Keyword | Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging Phased Array Rf Coil Parallel Imaging 9.4 T |
| Content Type | Text |
| Resource Type | Article |