NDLI: Screening for fetal anomalies by ultrasound at 14 and 21 weeks

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Screening for fetal anomalies by ultrasound at 14 and 21 weeks

Content Provider	Scilit
Author	D'ottauio, G. Meir, Y. J. Rustico, M. A. Pecile, Vanna Fischer-Tamaro, L. Conoscenti, G. Natale, R. Mandruzzato, G. P.
Copyright Year	1997
Description	Journal: Ultrasound in Obstetrics & Gynecology A prospective study of screening for fetal abnormalities and chromosomal defects was carried out by ultrasound examination at 13-15 weeks of gestation and 20-22 weeks; the first scan was performed transvaginally and the second transabdominally. During a 4-year period (1991-95), 3490 unselected consecutive pregnancies with a total of 3514 fetuses were examined. There were 21 chromosomally abnormal fetuses, including ten with trisomy 21, and, in 19 (90.5%), fetal defects were detected at the first and/or second ultrasound examination. The most effective marker for chromosomal defects was increased nuchal translucency thickness (> or = 4 mm) at the 13-15-week scan, which was present in seven of the ten fetuses with trisomy 21 and in six of the 11 with other chromosomal abnormalities.
Related Links	http://onlinelibrary.wiley.com/doi/10.1046/j.1469-0705.1997.10060375.x/pdf
Ending Page	380
Page Count	6
Starting Page	375
e-ISSN	14690705
DOI	10.1046/j.1469-0705.1997.10060375.x
Journal	Ultrasound in Obstetrics & Gynecology
Issue Number	6
Volume Number	10
Language	English
Publisher	Wiley-Blackwell
Publisher Date	1997-12-30
Access Restriction	Open
Subject Keyword	Journal: Ultrasound in Obstetrics & Gynecology Obstetrics and Gynecology Prenatal Diagnosis Ultrasound Screening Fetal Aneuploidies Transvaginal Sonography Nuchal Thickening Fetal Anomalies
Content Type	Text
Resource Type	Article

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