NDLI: CEREBRAL BLOOD-FLOW VELOCITY DURING THE FIRST WEEK OF LIFE OF PRETERM INFANTS AND NEURODEVELOPMENT AT TWO YEARS

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CEREBRAL BLOOD-FLOW VELOCITY DURING THE FIRST WEEK OF LIFE OF PRETERM INFANTS AND NEURODEVELOPMENT AT TWO YEARS

Content Provider	Scilit
Author	Bel, Frank Ouden, Lya Bor, Margot Stijnen, Theo Baan, Jan Ruys, Jan H.
Copyright Year	2008
Description	Journal: Developmental Medicine and Child Neurology Disturbances in perinatal cerebral perfusion appear to be associated with unfavourable neurodevelopmental outcome. Using transcutaneous Doppler technique, the authors investigated cerebral blood-flow velocity patterns in the anterior cerebral artery (ACA) of an intensive care-unit population of preterm infants during the first week of life. The results were correlated with neurodevelopmental outcome at two years of age. Children with major disability at two years of age had significantly higher pulsatility index (PI) values, mainly increased peak systolic flow velocity (PSFV), compared with children with normal or more favourable outcome. End diastolic flow velocity and area under the velocity curve values of the ACA did not differ between the groups, indicating that cerebrovascular resistance and cerebral blood-flow were not different. It is thought that the higher PI and PSFV values were caused by increased compliance of the vascular bed supplied by the ACA, possibly induced by congestion and oedema of the periventricular white-matter due to ischaemic lesions, which also cause periventricular leukomalacia.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8749.1989.tb04001.x/pdf
Ending Page	328
Page Count	9
Starting Page	320
ISSN	00121622
e-ISSN	14698749
DOI	10.1111/j.1469-8749.1989.tb04001.x
Journal	Developmental Medicine and Child Neurology
Issue Number	3
Volume Number	31
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2008-11-12
Access Restriction	Open
Subject Keyword	Journal: Developmental Medicine and Child Neurology Peripheral Vascular Disease Cerebral Blood Flow
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical) Pediatrics, Perinatology and Child Health Developmental Neuroscience

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