NDLI: Oral dantrolene and severe respiratory failure in a patient with chronic spinal cord injury

Content Provider	Scilit
Author	Javed, M. Bogdanov, A.
Copyright Year	2010
Description	Journal: Anaesthesia Oral dantrolene is used widely for the treatment of spasticity in patients with spinal cord injury. A 60-year-old patient in the rehabilitation phase following cervical spine injury presented with generalised weakness and deteriorating respiratory function, requiring intensive care admission, tracheal intubation and ventilation. He had bilateral basal lung collapse and a raised diaphragm and was on high-dose oral dantrolene. The cessation of dantrolene resulted in a dramatic recovery of respiratory function within two days. High-dose oral dantrolene can cause severe respiratory insufficiency and may present difficulties in the differential diagnosis of respiratory failure in patients with high cervical spinal cord injuries.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2010.06409.x/pdf
Ending Page	856
Page Count	2
Starting Page	855
e-ISSN	13652044
DOI	10.1111/j.1365-2044.2010.06409.x
Journal	Anaesthesia
Issue Number	8
Volume Number	65
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2010-06-17
Access Restriction	Open
Subject Keyword	Journal: Anaesthesia Spinal Cord Injury
Content Type	Text
Resource Type	Article

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Oral dantrolene and severe respiratory failure in a patient with chronic spinal cord injury