NDLI: Mechanobiology of limb musculoskeletal development

Content Provider	Scilit
Author	Arvind, Varun Huang, Alice H.
Copyright Year	2017
Description	Journal: Annals of the New York Academy of Sciences While there has been considerable progress in identifying molecular regulators of musculoskeletal development, the role of physical forces in regulating induction, differentiation, and patterning events is less well understood. Here, we highlight recent findings in this area, focusing primarily on model systems that test the mechanical regulation of skeletal and tendon development in the limb. We also discuss a few of the key signaling pathways and mechanisms that have been implicated in mechanotransduction and highlight current gaps in knowledge and opportunities for further research in the field.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730481/pdf
Ending Page	32
Page Count	15
Starting Page	18
e-ISSN	17496632
DOI	10.1111/nyas.13427
Journal	Annals of the New York Academy of Sciences
Issue Number	1
Volume Number	1409
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2017-08-22
Access Restriction	Open
Subject Keyword	Journal: Annals of the New York Academy of Sciences Developmental Biology
Content Type	Text
Resource Type	Article

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