NDLI: Copper Hydride Catalyzed Hydroamination of Alkenes and Alkynes

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Copper Hydride Catalyzed Hydroamination of Alkenes and Alkynes

Content Provider	Scilit
Author	Pirnot, Michael T. Wang, Yi-Ming Buchwald, Stephen L.
Copyright Year	2015
Description	Journal: Angewandte Chemie International Edition Over the past few years, CuH-catalyzed hydroamination has been discovered and developed as a robust and conceptually novel approach for the synthesis of enantioenriched secondary and tertiary amines. The success in this area of research was made possible through the large body of precedent in copper(I) hydride catalysis and the well-explored use of hydroxylamine esters as electrophilic amine sources in related copper-catalyzed processes. This Minireview details the background, advances, and mechanistic investigations in CuH-catalyzed hydroamination.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782926/pdf
Ending Page	57
Page Count	10
Starting Page	48
ISSN	14337851
e-ISSN	15213773
DOI	10.1002/anie.201507594
Journal	Angewandte Chemie International Edition
Issue Number	1
Volume Number	55
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2015-12-10
Access Restriction	Open
Subject Keyword	Journal: Angewandte Chemie International Edition Organic Chemistry Asymmetric Catalysis Chiral Amine Synthesis Copper(i) Hydride
Content Type	Text
Resource Type	Article
Subject	Chemistry Catalysis

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