NDLI: Cervicovaginal involvement in pemphigus vulgaris: a clinical study of 77 cases

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Cervicovaginal involvement in pemphigus vulgaris: a clinical study of 77 cases

Content Provider	Scilit
Author	Akhyani, M. Chams‐Davatchi, C. Naraghi, Z. Daneshpazhooh, M. Toosi, S. Asgari, M. Malekhami, F.
Copyright Year	2007
Description	Journal: British Journal of Dermatology Pemphigus vulgaris (PV) is an autoimmune blistering disease which is known to involve the female genital tract, but the frequency at which this occurs is unknown. There are few reports in the literature of the cytological appearance of PV on cervicovaginal smears. To evaluate involvement of the female genital tract and the appearance of cervicovaginal Papanicolaou (Pap) smears in PV. The study included 77 patients with PV who attended between April 2005 and February 2007. Each patient was subjected to gynaecological examination and cervicovaginal Pap smear. Genital lesions were observed in 39 patients (51%). Of these, the labia minora were involved in 36 patients (92%), the labia majora in 11 (28%), the vagina in 14 (36%) and the cervix in six (15%). Cervicovaginal Pap smears of 20 of 77 patients (26%) showed PV. Of 72 satisfactory Pap smears, the cervical Pap smear was normal in 25 patients (35%), inflammatory in 43 patients (60%), and dysplastic (low-grade squamous intraepithelial neoplasia) in four patients (6%). Involvement of the female genital tract with PV might not be as infrequent as was previously thought; it is probably the second most common mucosal site of PV after the oral mucosa. Genital lesions may be missed and the need for thorough pelvic examination should not be overlooked.
Ending Page	482
Starting Page	478
ISSN	2573508X
e-ISSN	13652133
DOI	10.1111/j.1365-2133.2007.08356.x
Journal	British Journal of Dermatology
Issue Number	3
Volume Number	158
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2007-12-07
Access Restriction	Open
Subject Keyword	Journal: British Journal of Dermatology Papanicolaou Smear Pemphigus Vulgaris
Content Type	Text
Resource Type	Article

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