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Simultaneous acquisition of gradient echo/spin echo BOLD and perfusion with a separate labeling coil
| Content Provider | Scilit |
|---|---|
| Author | Glielmi, C. B. Xu, Q. Craddock, R. C. Hu, X. |
| Copyright Year | 2010 |
| Description | Journal: Magnetic Resonance in Medicine Arterial spin labeling-based cerebral blood flow imaging complements blood oxygenation level dependent (BOLD) imaging with a measure that is more quantitative and has better specificity to neuronal activation. Relative to gradient echo BOLD, spin echo BOLD has better spatial specificity because it is less biased to large draining veins. Although there have been many studies comparing simultaneously acquired cerebral blood flow data with gradient echo BOLD data in fMRI, there have been few studies comparing cerebral blood flow with SE BOLD and no study comparing all three. We present a pulse sequence that simultaneously acquires cerebral blood flow data with a separate labeling coil, gradient echo BOLD, and spin echo BOLD images. Simultaneous acquisition avoids interscan variability, allowing more direct assessment and comparison of each contrast's relative specificity and reproducibility. Furthermore, it facilitates studies that may benefit from multiple complementary measures. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978273/pdf |
| Ending Page | 1831 |
| Page Count | 5 |
| Starting Page | 1827 |
| e-ISSN | 15222594 |
| DOI | 10.1002/mrm.22554 |
| Journal | Magnetic Resonance in Medicine |
| Issue Number | 6 |
| Volume Number | 64 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-07-20 |
| Access Restriction | Open |
| Subject Keyword | Journal: Magnetic Resonance in Medicine Radiology, Nuclear Medicine and Imaging Cerebral Blood Flow Spin Echo Magnetic Resonance Imaging |
| Content Type | Text |
| Resource Type | Article |