NDLI: SYNTHESIS OF AN OPEN-CHAIN ASYMMETRICAL CYSTINE PEPTIDE CORRESPONDING TO THE SEQUENCE A18-21 -B19-26 OF BOVINE INSULIN BY SOLID PHASE FRAGMENT CONDENSATION

Please wait, while we are loading the content...

SYNTHESIS OF AN OPEN-CHAIN ASYMMETRICAL CYSTINE PEPTIDE CORRESPONDING TO THE SEQUENCE A18-21 -B19-26 OF BOVINE INSULIN BY SOLID PHASE FRAGMENT CONDENSATION

Content Provider	Scilit
Author	Kullmann, W. Gutte, B.
Copyright Year	2009
Description	Journal: International journal of peptide and protein research An insulin fragment containing residues A 18-21 and B 19-26 linked by the disulfide bond between residues A 20 and B 19 was synthesized. The sequence B 21-26 was assembled on a solid support by the Merrifield technique. The protected fragments A 18-21 and B 19-20 were prepared by conventional methods. After forming the disulfide bridge through cleavage of the S-thiocarbonate derivative of A 18-21 by the thiol peptide B 19-20, the resulting assymmetrical cystine peptide A 18-21--B 19-20 was coupled via the carboxyl group of residue B 20 to the free NH 2-terminal amino group of the protected B 21-26 resin. The product was deprotected, cleaved from the resin, and purified to give the homogenous dodecapeptide A 18-21--B 19-26.
Related Links	http://onlinelibrary.wiley.com/doi/10.1111/j.1399-3011.1978.tb02863.x/pdf
Ending Page	26
Page Count	10
Starting Page	17
ISSN	03678377
DOI	10.1111/j.1399-3011.1978.tb02863.x
Journal	International journal of peptide and protein research
Issue Number	1
Volume Number	12
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2009-01-12
Access Restriction	Open
Subject Keyword	Journal: International journal of peptide and protein research Endocrinology and Metabolism Asymmetrical Cystine Peptide Resin Cooh‐terminal Insulin Fragment Selectively Removable Nα‐protecting Groups Solid Phase Fragment Condensation
Content Type	Text
Resource Type	Article
Subject	Biochemistry

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Fmoc-Compatible Solid-Phase Peptide Synthesis of Long C-Terminal Peptide Thioesters

Semisynthetic studies on bovine pancreatic ribonuclease

SOLID-PHASE PEPTIDE SYNTHESIS OF SOMATOSTATIN USING MILD BASE CLEAVAGE OF Nα-9- FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS

STABLE ISOLATED SYMMETRICAL ANHYDRIDES OF Nα-9-FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS IN SOLID-PHASE PEPTIDE SYNTHESIS:

Solid-phase synthesis of chicken vasoactive intestinal peptide by a mild procedure using Nα-9-fluorenylmethyloxycarbonyl amino acids

Preparation and properties of Nα-Bpoc-amino acid pentafluorophenyl esters

SOLID PHASE SYNTHESIS WITHOUT REPETITIVE ACIDOLYSIS

New mild acid-labile protecting groups for the guanidino function of Nα-fluorenylmethoxycarbonyl-l-arginine in solid-phase peptide synthesis: 10, 11-dihydro-5H-dibenzo[a, d]. cyclohepten-5-yl, 2-methoxy-10, 11-dihydoro-5H-dibenzo[a, d]. cyclohepten-5-yl a

Effects of Hexapeptide, a Compound Analogous to Insulin B Chain Fragment B-21-26(DP-432) on the Glucose Uptake into the Perfused Hind Limb of Rats

SYNTHESIS OF AN OPEN-CHAIN ASYMMETRICAL CYSTINE PEPTIDE CORRESPONDING TO THE SEQUENCE A18-21 -B19-26 OF BOVINE INSULIN BY SOLID PHASE FRAGMENT CONDENSATION

Similar Documents

Fmoc-Compatible Solid-Phase Peptide Synthesis of Long C-Terminal Peptide Thioesters

Semisynthetic studies on bovine pancreatic ribonuclease

SOLID-PHASE PEPTIDE SYNTHESIS OF SOMATOSTATIN USING MILD BASE CLEAVAGE OF Nα-9- FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS

STABLE ISOLATED SYMMETRICAL ANHYDRIDES OF Nα-9-FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS IN SOLID-PHASE PEPTIDE SYNTHESIS:

Solid-phase synthesis of chicken vasoactive intestinal peptide by a mild procedure using Nα-9-fluorenylmethyloxycarbonyl amino acids

Preparation and properties of Nα-Bpoc-amino acid pentafluorophenyl esters

SOLID PHASE SYNTHESIS WITHOUT REPETITIVE ACIDOLYSIS

New mild acid-labile protecting groups for the guanidino function of Nα-fluorenylmethoxycarbonyl-l-arginine in solid-phase peptide synthesis: 10, 11-dihydro-5H-dibenzo[a, d]. cyclohepten-5-yl, 2-methoxy-10, 11-dihydoro-5H-dibenzo[a, d]. cyclohepten-5-yl a

Effects of Hexapeptide, a Compound Analogous to Insulin B Chain Fragment B-21-26(DP-432) on the Glucose Uptake into the Perfused Hind Limb of Rats

SYNTHESIS OF AN OPEN-CHAIN ASYMMETRICAL CYSTINE PEPTIDE CORRESPONDING TO THE SEQUENCE A18-21 -B19-26 OF BOVINE INSULIN BY SOLID PHASE FRAGMENT CONDENSATION