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Detection of Antisperm Antibodies on the Surface of Motile Spermatozoa. Comparison of the Immunobead Binding Technique (IBT) and the Mixed Antiglobulin Reaction (MAR)
| Content Provider | Scilit |
|---|---|
| Author | Meinertz, Helle Bronson, Richard |
| Copyright Year | 1988 |
| Description | Journal: American Journal of Reproductive Immunology Investigators testing for antisperm antibodies have recently focused on tests that detect the Ig classes of the sperm-bound antibodies. The aim of this study was to compare the sensitivity of two of these tests, viz. the immunobead binding technique (IBT) and the mixed antiglobulin reaction (MAR). Twenty-one male or female sera were tested for IgG and IgA antisperm antibodies with the IBT and the MAR. The sera were selected on the basis of the IBT results, and the MAR was carried out without knowledge of these results. For IgG antisperm antibodies, there was a highly significant correlation between the two tests (P = 0.0043), whereas, for IgA antisperm antibodies, the correlation was poor (P = 0.2951), because the IBT revealed a positive reaction for IgA in sera in which no such antibodies could be detected by the MAR. |
| Related Links | http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0897.1988.tb00247.x/pdf |
| Ending Page | 123 |
| Page Count | 4 |
| Starting Page | 120 |
| e-ISSN | 16000897 |
| DOI | 10.1111/j.1600-0897.1988.tb00247.x |
| Journal | American Journal of Reproductive Immunology |
| Issue Number | 4 |
| Volume Number | 18 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 1988-12-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: American Journal of Reproductive Immunology Obstetrics and Gynecology Antisperm Antibodies Immunobead Binding Technique (ibt) Mixed Antiglobulin Reaction (mar) |
| Content Type | Text |
| Resource Type | Article |